ATRA and arsenic trioxide versus ATRA and idarubicin for newly diagnosed, non...
New research demonstrates the efficacy of the first curative treatment for acute promyelocytic leukemia (APL) that does not include chemotherapy, marking an important step toward front-line use of...
View ArticleGenotype predicts treatment related mortality (TRM) in African-American and...
New research suggests that the presence of a specific genetic marker, known as WT1 SNP rs16754, may be associated with reduced toxicity from chemotherapy in African-American and Asian children with...
View ArticleGenetic susceptibility to anthracycline-related congestive heart failure...
Researchers have identified specific genetic factors that are associated with heart failure in patients who have undergone hematopoietic stem cell transplantation (HCT) for blood cancer.
View ArticleStudies assess genetics, modified treatment to improve outcomes, reduce toxicity
Research identifying genetic factors that affect survival of patients with blood cancers and evaluating the effectiveness of modified treatment strategies to improve outcomes while reducing toxicity...
View ArticleA large-scale trial testing the intensity of cytoreductive therapy to prevent...
In the first randomized clinical trial assessing the proper target hematocrit level, or percentage of red blood cells that should be maintained in patients with polycythemia vera (PV), researchers have...
View ArticleNew stem cell research, transplant strategies show promise to improve...
Studies of stem cell biology and transplant approaches presented today at the 54th Annual Meeting of the American Society of Hematology (ASH) illustrate how the use of advanced modeling techniques is...
View ArticleTargeting histone deacetylases as a new strategy for graft versus host...
New research shows that the addition of the oral anti-cancer agent vorinostat to standard therapy given before, during, and after hematopoietic stem cell transplantation (HSCT) may safely reduce the...
View ArticleNovel therapeutic agents provide hope for patients with hard-to-treat blood...
Encouraging safety and efficacy data on novel and emerging therapies presented at the 54th Annual Meeting of the American Society of Hematology (ASH) signal an important step forward in the development...
View ArticleCombination therapy using JAK2 and HSP90 inhibitors increased efficacy in...
Researchers have demonstrated that combination therapy with PU-H71 and ruxolitinib increases the durability and effectiveness of a treatment that had previously shown limited utility for patients with...
View ArticleSurvey shows breakthrough medical research relies heavily on NIH funding
A survey highlighting the correlation between today's cutting edge medical research and the National Institutes of Health (NIH) funding was released today at the 54th Annual Meeting of the American...
View ArticleCultural, social factors identified as barriers to minority participation in...
New research examining the role of race and ethnicity in an individual's decision to become a donor for hematopoietic cell transplantation (HCT) identifies several factors associated with varied...
View ArticleASH international clinical collaboration replicates high cure rate of APL in...
Data published online today in Blood, the Journal of the American Society of Hematology (ASH) describe the work of an ASH international clinical network collaborative focused on modernizing treatment...
View ArticleRisk of leukemia after cancer chemotherapy persists
While advancements in cancer treatment over the last several decades have improved patient survival rates for certain cancers, some patients remain at risk of developing treatment-related leukemia,...
View ArticleCord blood effective alternative to matched donor stem cells for kids with...
Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating...
View ArticleKey bone marrow protein identified as potential new leukemia treatment target
A new study on how the progression of acute lymphocytic leukemia (ALL) is influenced by the bone marrow environment has demonstrated for the first time that targeting a specialized protein known as...
View ArticleLeading leukemia experts: High leukemia treatment costs may be harming patients
The increasing cost of treatments for chronic myeloid leukemia (CML) in the United States has reached unsustainably high levels and may be leaving many patients under- or untreated because they cannot...
View ArticleImproved chemo regimen for childhood leukemia may offer high survival, no...
Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates...
View ArticleTechnologies for monitoring remaining leukemia after treatment may help...
New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately...
View ArticleNew research suggests cutting calories may improve response to cancer treatment
New research suggests that restricting calories for a defined period of time may improve the success of cancer treatment, offering valuable new data on how caloric intake may play a role in programmed...
View ArticleResearch shows genetic anti-inflammatory defect predisposes children to lymphoma
New research shows that children with an inherited genetic defect in a critical anti-inflammatory pathway have a genetic predisposition to lymphoma. Results of the study, published online today in...
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